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What is chloroquine?
Chloroquine (also known as chloroquine phosphate) is an antimalarial medicine. It is available in the
United States by prescription only. It is sold under the brand name Aralen, and it is also sold as a generic
medicine. It is available in tablets of two sizes: 150mg base (250mg salt) and 300mg base (500mg salt).
You should know that the 150mg base tablet is the same as the 250mg salt tablet and the 300mg base
tablet is the same as the 500mg salt tablet. It is just two different ways of describing the same thing.
Chloroquine can be prescribed for either prevention or treatment of malaria. This fact sheet provides
information about its use for the prevention of malaria infection associated with travel.
Center for Global Health Division of Parasitic Diseases and Malaria
Who can take chloroquine?
Chloroquine can be prescribed to adults and children of all ages. It can also be safely taken by pregnant
women and nursing mothers. Who should not take chloroquine?
People with psoriasis should not take chloroquine. How should I take chloroquine?
Both adults and children should take one dose of chloroquine per week starting at least 1 week before
traveling to the area where malaria transmission occurs. They should take one dose per week while
there, and for 4 consecutive weeks after leaving. The weekly dosage for adults is 300mg base
(500mg salt). Your doctor will have calculated the correct weekly dose for your child based on the child’s weight. The
child’s dose should not exceed the adult dose of 300mg base (500mg salt) per week.
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Antimalarial drugs are available in the United States by prescription only. Medicines should be obtained
at a pharmacy before travel rather than in the destination country. Buying medications abroad
has its risks: the drugs could be of poor quality, contaminated, or counterfeit and not protect you
against malaria. In what parts of the world can chloroquine be used for prevention of malaria in travelers?
There are only a few places left in the world where chloroquine is still effective including parts of
Central America and the Caribbean. CDC keeps track of all the places in the world where
malaria transmission occurs and which malaria drugs that are recommended for use in each place.
This information can be found using the malaria map on the CDC website: http://www.cdc.gov/
malaria/map/index.html. This map shows an approximation of the parts of the world where malaria
transmission occurs. For more detailed information about the occurrence of malaria
transmission in specific countries, please use the interactive Malaria Map Application.
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